The Defense Medical Epidemiology Database Reports Massive Increases In Adverse Reactions And How CBD Treats Each Disease.
CBD and Hypertension (+2181% Increase)
Original Article www.healthline.com/health/cbd-for-blood-pressure#safety
Hypertension (high blood pressure) can cause serious health problems such as heart attack and stroke. Many people with hypertension don’t know they have it because there are rarely any symptoms. It is important to check your blood pressure regularly.
Cannabidiol (CBD), which can lower blood pressure, may be an option for you if you suffer from hypertension. Here are some tips and research to help you find a few products.
Blood pressure refers to the pressure of blood against the walls and arteries. It’s normal for blood pressure to fluctuate over time, but consistently high levels can be dangerous.
Two types of hypertension exist:
- Primary hypertension is the most common. Although it is gradual and has no identifiable cause, it can be caused by genetics, body changes, high body weight, or other factors.
- Secondary hypertension can develop quickly and be much more severe. There are many causes for it, such as kidney disease, congenital hearts defects, and thyroid issues. It can also be caused by certain stimulants and medications, such as cocaine or amphetamines.
Hypertension can often be silent and you may not feel symptoms until it becomes more severe. symptoms could include:
- Breathing difficulty
- chest pain
- Vision changes
- Urine containing blood
These symptoms should be reported immediately to a doctor.
The potential health benefits of CBD are acknowledged by both the Food and Drug Administration(FDA)Trusted Source and World Health Organization (WHO).
2017 WHO reportTrusted Source claims CBD is generally well-tolerated, with no signs of misuse or dependence.
The FDA acknowledges that further research is necessary and points out that there are still many questions regarding CBD’s safety. It also notes that certain CBD products may be inaccurately labeled or have questionable quality.
You should be aware that CBD can cause side effects in some people.
- Changes in appetite or weight
Research from 2012 Trusted source about anxiety and cannabinoids suggests that some may have biphasic effects, which means they produce different effects depending upon the dosage.
A 2011 study trusted source showed that THC, either alone or in combination, can sometimes cause high blood pressure.
It’s important to remember that CBD can interact with certain medications, such as hypertension medication trusted Source. Talk to your doctor before you consider CBD for high blood pressure management.
CBD and Diseases of the nervous system (+1048% Increase)
Full article at: www.cbdbotanicalsinc.com/how-does-cbd-affect-the-nervous-system/
What Can CBD Do to the Nervous System?
CBD has many positive effects on the nervous system. CBD can be described as a powerful anti-inflammatory. Anti-inflammatory CBD can be taken orally, or topically. It protects the nervous system and ensures that it is effective.
CBD is known to be a powerful treatment for disorders and conditions that can harm the nervous system. A recent study has shown that CBD inhibits anandamide, which in turn increases protective brain synapses. Another study has shown that CBD can be used to treat epileptic seizures. FDA approval has been granted for CBD medication.
It is evident that CBD positively affects your nervous system in a variety of ways, both in a general sense and through the lens of certain dilapidating medical conditions.
CBD Products for the Nervous Systems
There are several products that can help with inflammation and other conditions that affect the nervous system.
Asteroid Gummies can be a great option for those suffering from chronic pain conditions that impact their nervous system throughout the day. These CBD isolate gummies can provide immediate pain relief and enhanced focus. They are vegan and all-natural.
Isolate capsules are also an excellent option for people with nervous system conditions. This delivery method delivers a consistent amount of CBD and powdered coconut oils, which make the benefits of CBD more bioavailable.
CBD positively affects the nervous system
Recent research shows that CBD positively impacts the nervous system. You can find out more about CBD and how it can help you here. You don’t have to wonder how CBD affects your nervous system.
CBD and Malignant neoplasms of the esophagus (+894% Increase)
Full Article at www.ncbi.nlm.nih.gov/pmc/articles/PMC7693730/
Cannabinoids that contain plant extracts have been used as herbal medicine since at least 500 BC. The medical and health-related uses of CBD (or cannabidiol) have received a lot of attention in recent years. We will be reviewing the latest findings supporting CBD’s future development as an anti-cancer drug.
Recently, cannabinoids, such as cannabidiol (CBD) and D9-tetrahydrocannabinol (THC), have been the subject of intensive research and heavy scrutiny. Cannabinoids include a variety of organic molecules. These can be synthesized in laboratories and extracted from the Cannabis Sativa plant. They share similar chemical structures and protein binding profiles. There are some differences in the mechanisms of action and clinical uses, and these will be briefly contrasted and contrasted in this review. This review will focus on CBD’s mechanism of action and potential applications for cancer therapy.
Keywords: cannabinoids, cannabidiol, CBD, anti-cancer drug
CBD and Mulitple sclerosis (+680% Increase)
CBD has many benefits for MS
A recent meta-analysis found that CBD and cannabinoids (including CBD) are “probably effective” in relieving certain MS symptoms, such as pain and abnormal muscle tightness (spasticity), but not “probably effective” for treating muscle cramps or incontinence. 3
Additional research supports CBD for MS. These are the key findings
- According to a 2018 scientific review, CBD supplementation can reduce pain, fatigue, and inflammation in MS patients, as well as improve mobility. The authors concluded that CBD supplementation would be beneficial for MS patients. 4
- Sativex (nabiximols), which is a CBD nasal spray, was found to reduce pain, spasticity, and frequent urination among patients with MS. 5
- Two 2021 medical reviews have shown that CBD regulates the immune system in animals, which helps to reduce the symptoms of MS. 6
Although more research is required, it’s possible that CBD and cannabis-derived medicines could be used in the future to treat MS progression, not just symptoms.
CBD and Malignant neoplasms of digestive organs (+624% Increase)
Original Article at Cannabinoids and the digestive tract – PubMed (nih.gov)
In the digestive tract, there is evidence for the presence of high levels of endocannabinoids (anandamide and 2-arachidonoylglycerol) and enzymes involved in the synthesis and metabolism of endocannabinoids. Immunohistochemical and immunohistochemical tests have demonstrated the presence of CB1 receptors at the myenteric, submucosal, and alimentary tract nerve plexuses. Pharmacological studies have demonstrated that activation of CB1 receptors result in relaxation of the lower Oesophageal Sphincter, inhibition gastric motility, acid secretion, and intestinal motility. CB1-induced intestinal motility and secretion are due to decreased acetylcholine from the enteric nerves. Endocannabinoids, on the other hand, stimulate primary sensory neurons in the intestinal via their vanilloid VR1 receptor. This results in enteritis, and increased motility. Endogenous cannabinoid systems have been shown to play a role in the physiological control and pathophysiological states of colonic motility. Cannabinoids have antiemetic properties that are mediated through activation of CB1 receptors in the central and peripheral. The potential for pharmacological modulation by the endogenous cannabis cannabinoid system to treat a variety of gastrointestinal conditions, such as nausea and vomiting, gastric and intestinal ulcers, secretory diarrhea, paralytic ileus and inflammatory bowel disease, colon carcinoma, and gastro-oesophageal disorders, could be a new therapeutic target.
CBD and Guillain-Barre syndrome (+551% Increase)
Orginal Article at CBD & Guillain Barre (rusticoils.com)
What can CBD do for Guillain Barre Syndrome?
Guillain Barre can be characterized by many symptoms, as we have discussed. Pain, inflammation, sensation changes, muscle spasms, etc. It can be very debilitating. CBD has been discussed for years because of its neuroprotective properties. In fact, the US government issued a patent for CBD in 1996. There are many videos showing CBD being used to treat epilepsy, Parkinson’s, and Parkinson’s. When you ask Guillain-Barre patients, the most popular benefit of CBD for Guillain-Barre is the relief from pain and inflammation caused by the damaged nerves.
Your Endocannabinoid Systems are activated by CBD. This is a group that can be found on almost every type of cell in the human body. These receptors send signals to all systems of the body to maintain and promote homeostasis. CBD activates these receptors to reduce the levels of sensitizers in the damaged cells. There are a few ways CBD can be helpful.
- Stabilize the nerve to prevent it from over-firing pain signals.
- Reduce inflammation in nerve cells and surrounding tissues
- Relax the immune system in surrounding areas and prevent the release of inflammatory chemicals.
The bottom line is that your Endocannabinoid System, which is an amazing system, is constantly working to maintain balance within your body. This is the key to maintaining Homeostasis.
CBD and Breast Cancer (+487% Increase)
The most shocking thing I discovered while researching these blogs was that our bodies have cannabidiol-like receptors, which are the targets for hormonal therapies that we use to treat hormone-sensitive breast cancer.
To begin, is cannabis safe? A review of 25 English-language pooled research studies concluded that marijuana use is safe. However, some research has suggested that it could increase the risk for testicular cancer.
In 2020, a paper was published by the Journal of Cannabis Research. Yes, that journal exists! It was found that medical cannabis is being used for many different health conditions, which highlights the need to further research its clinical benefits. The most popular uses of medical cannabis include improving mental and physical health, sleep, pain relief, and the reduction of neurological and cancer-related side effects.
The 2020 Study, published in the Journal Pharmaceuticals, evaluated the short-term results of medical cannabis treatment prescribed to cancer patients. THC was found to be more effective for sleep than CBD. CBD oils were found to be more effective in reducing the collateral effects of cancer treatments. According to the American Pain Society guidelines, cannabis oils for pain should contain low levels of THC as well as high levels CBD.
Dr.William Courtney Cures Imoperale Brain Tumor on Baby With CBD.
CBD and Demyelinating (+487% Increase)
Inflammation in the central nervous system (CNS), is complex and requires a variety of molecules and effectors. It also requires the transmigration of blood cells across the blood-brain barrier and activation of resident immune cells. Cannabidiol is a non-psychotropic cannabis cannabinoid component of C Annabis sativa. It has powerful anti-inflammatory and immune-suppressive qualities. It is not clear how this compound modulates the adverse effects of inflammation in TMEV induced demyelinating disorder (TMEVIDD). This viral model of multiple sclerosis (MS) shows that CBD reduces blood leukocyte transmigration by downregulating the expression of vascular cell adhesion molecules-1 (VCAM-1), CCL2, and CCL5, and the proinflammatory Cytokine IIL-1b as well as attenuating activation of microglia. CBD administration during viral infection has long-lasting effects. It reduces motor impairments in chronic phases of the disease and increases pro-inflammatory cell cytokine generation. The anti-inflammatory properties of CBD are partially blocked by the A antagonist ZM241385, which partially blocks the protective effects of CBD during the initial stages. Our findings demonstrate the therapeutic potential of CBD for treating inflammatory diseases.
CBD and Malignant neoplasms of thyroid and other endocrine glands (+474% Increase)
Original article found at The effects of cannabinoids on the endocrine system – PubMed (nih.gov)
Cannabinoids, which are derivatives of cannabis plants, have the highest potent bioactive components. Tetrahydrocannabinol is the most potent. Cannabinoids can be found in marijuana, hashish, and hashish oil. These compounds interact with the cannabinoid receptors CB1 or CB2. CB1 and CB2 are the most common types of receptors. They are located in the central nervous systems, adipose tissues, and many visceral organs including the majority of endocrine ones. Type 2 cannabinoid receptors (CB2) are located in the peripheral nervous systems (peripheral neuro endings) as well as on the surface cells of the immune system. These receptors have been receiving increasing attention, both in terms of their role and the endogenous ligands. Endogenous cannabinoids have been shown to regulate food intake and energy homeostasis. They also have an important impact on the endocrine systems, including the activity of the pituitary, adrenal cortex, and thyroid glands. The interrelationships between the endocrinoid system, the activity of the body’s endocrine system, and infertility treatment, as well as prevention and treatment of cardiovascular diseases, such as diabetes and obesity, may provide a therapeutic target.
Keywords: CB1 receptor; cannabinoid system; endocannabinoids; endocrine system.
CBD and Female Infertility (+472% Increase)
Original article at CBD and Fertility (scrcivf.com)
CBD, Endocannabinoids, and Fertility
It seems that the list of conditions CBD can treat is growing by the day. It can relieve anxiety, chronic pain, seizures, and even fertility. This is a great question. However, we don’t have a clear answer.
CBD is a fascinating product, and one reason it’s considered a good product to help with fertility. Its chemical structure is similar to some hormones that our bodies produce called endocannabinoids.
The complex endocannabinoid (ECS), which is still being studied by experts, is not something we know much about. They have linked it to many important body processes, including sleep, pain, immune system response, and reproductive system. The ECS receptors allow CBD and THC to interact with the body. They can relieve pain, inflammation, seizures, stress, and other symptoms.
The sperm and female reproductive tract contains endocannabinoid receptors. It is believed that these receptors can increase a male sperm’s ability for follicle maturation, ovarian function, and fertilization of an egg. CBD is a natural way of increasing fertility. It has minimal side effects. This theory is not supported by strong evidence.
We still have much to learn about the Endocannabinoid System, its role as a fertility regulator, and how it interacts (and is affected by) CBD.
CBD Pumonary embolism (+468% Increase)
Original Article at Is CBD Oil a Cure for Deep Vein Thrombosis? (nashvilleveincenter.com)
CBD Oil only relieves the symptoms
CBD oil has been shown to be effective in relieving symptoms of DVT. Particularly, inflammation and pain. A study published in The Journal of Pharmacology and Experimental Therapeutics showed that CBD oil has anti-inflammatory properties. This oil can help reduce swelling caused by deep vein thrombosis. The study found no side effects.
Let’s take an in-depth look at DVT and how it can be treated.
What is DVT? How does it happen?
Deep vein thrombosis ( DVT) refers to a blood clot that forms in deep veins in the body and blocks blood flow. What is a deep venous? It is distinct from an artery. These veins are found deep within the body, as opposed to being located near the surface. DVT is most likely to occur in the pelvic or leg area. Any size clot is possible, large or small. The clot can cause blood flow to stop completely or partially. There may be redness or pain. Sometimes, symptoms are not apparent.
CBD and Migraines (+452% Increase)
Original article found at CBD and Migraines | Migraine.com
What does CBD do for migraines?
2,3 There is not much scientific data on CBD and its effects on migraine mainly because medical research on CBD and Cannabis has been banned by the DEA as a schedule 1. hmmm, I wonder why?
. However, there are some indications that CBD could be beneficial for patients suffering from migraine. 1
Researchers know that CBD and THC both have an effect on a neurotransmitter called serotonin. This can play a role in migraine. Researchers know that THC and CBD both affect a neurotransmitter known as a href=”https://migraine.com/living-with-migraine/migraine-and-sleep-disorders”>serotonin, which can play a role in migraine. 2
CBD Ovarian Dysfunction (+437% Increase)
Original article at Ovarian Dysfunction – Cannabis THC: CBD Ratios – Cannakeys
Description of Ovarian Dysfunction
Ovarian dysfunction can occur due to an imbalance in reproductive hormones such as an over-abundant presence of androgen (male hormone). For instance, polycystic ovary syndrome (PCOS) is a hormonal disorder that can affect a woman’s ability to conceive offspring. Signs and symptoms of PCOS commonly include dysmenorrhea (painful or difficult menstruation), an excess of androgen, fluid build-up in a number of follicles (sacs) in the ovaries resembling a fluid-filled cyst thus the name polycystic ovary. Within the orthodox medical system, the exact cause is unknown but contributing factors may include hormonal imbalances (esp. an excess of androgens), chronic inflammation in the architecture of the ovaries, and genetic predisposition.
CBD Interaction with Pharmaceutical Drugs
- CBD may alter action on metabolic enzymes (certain drug-transport mechanisms), and as such may alter interactions with other drugs, some of which may produce therapeutic or adverse effects. For instance, CBD interacts with the enzymes cytochrome P450 3A4 and cytochrome P450 2C19, increasing the bioavailability of anti-epileptic drugs such as clobazam (a benzodiazepine). This makes it possible to achieve the same results at significantly lower dosages, reducing treatment costs and risks of adverse effects.
- Groups of drugs affected include anti-epileptic drugs, psychiatric drugs, and drugs affecting metabolic enzymes, for example.
- Clinical observations suggest no likely interactions with other pharmaceuticals at a total daily dose of up to 100mg CBD
CBD And Testicular Cancer (+369% Increase)
Original Article Found At Cannabinoids and Testicular Cancer (medicalmarijuana.com)
Testicular cancer refers to cancer that begins in the testicles (the male reproductive glands located in your scrotum).
Risk factors, causes, and incidence
It is not known what causes testicular cancer. There is no connection between testicular cancer and vasectomy. The following factors may increase the risk of testicular cancer in men:
- Abnormal testicle development
- Testicular cancer history
- History of the undescended testicle
- Klinefelter syndrome
Exposure to chemicals or HIV infection are other possible causes. Risk factors include a family history of testicular carcinoma.
Between the ages 15 and 35, testicular cancer is the most prevalent form of cancer. It can also occur in older men and in rare cases in younger boys. This type of cancer is more common in white men than it is in African-American or Asian-American men. Seminomas are the most common type of testicular carcinoma. These cancers are caused by germ cells, which are the cells that produce sperm. Testicular cancer can be caused by any type of cell found in the testicles. However, over 95% of all testicular tumors are germ cell tumors. Testicular germ cell tumors are often too numerous in number.
CBD and Tachycardia (+303% Increase)
Original Article Found at CBD Oil for Postural Orthostatic Tachycardia Syndrome (POTS) – PandaCBD2% Increase)
The popularity of CBD is increasing all over the globe, making it a great time to explore this alternative health product. There is increasing evidence that CBD has positive effects on anxiety, chronic pains, inflammation, epilepsy, as well as other mental and physical ailments.
POTS (also known as Postural Orthostatic Tachycardia syndrome) is one of these conditions. Is there any benefit to CBD oil for Postural Orthostatic Tachycardia Syndrome patients? This article will address this question.
What is POTS?
POTS (Postural Orthostatic Tachycardia Syndrome) is a condition that affects the body’s blood circulation. It affects your nervous system, including both the autonomic as well as the sympathetic systems. The first controls and regulates bodily functions while the second aids in the fight or flight response.
POTS doesn’t allow your body to stabilize blood flow within your vessels into a steady rate. The symptoms of POTS can be caused by standing from a reclining position. They can also be reduced by sitting, lying down, or resting. POTS is characterized by fainting, lightheadedness and discomfort.
It is important to remember that every case of POTS will be unique and different for each person. The symptoms of POTS can vary from one patient to another. Sometimes, a change in diet or physical activity can be helpful to manage and subdue symptoms.
Who is at greatest risk of POTS?
The United States currently has approximately half a million POTS patients. The majority of patients with POTS are women aged between 13 and 50. People with a history of mononucleosis can get POTS. It is also common in those with autoimmune conditions. Because it affects the immune systems, people with Sjogren’s syndrome or Celiac disease are at greater risk of developing POTS. Lab tests can detect POTS.
What is CBD?
Many people have negative opinions of CBD because it is often referred to as THC or marijuana. Despite being somewhat similar, there are important differences between CBD and THC. Cannabidiol (or CBD) is extracted from Cannabis Sativa. CBD doesn’t produce a high like THC. Instead, it produces the same effects as THC but without the mind-altering effects. It is a great option for those who desire the physical effects of CBD but don’t want to feel the hallucinogenic effects of THC.
How is CBD oil made
CBD is extracted from Cannabis Saativa. It is then mixed with carrier oils (hemp and coconut oils). Because they are the most effective at binding to the chemical compound, CBD is diluted with these carrier oils. But oils are just one way to store CBD. You can also find CBD-rich products such as lotions, edibles, and bath bombs.
What does CBD oil do to treat POTS?
Recent research has shown that the body has an endocannabinoid (or ECS) system which regulates body functions like sleep and pain. This system produces endocannabinoids that bind to the cannabinoid receptors in the nervous system. Some research has shown that CBD can affect the body’s endocannabinoid receptors, which in turn can decrease inflammation and pain. This is especially beneficial for those suffering from POTS (an autonomic condition that affects the nervous system).
Although no research has proven CBD to cure POTS, CBD is well-known for treating symptoms such as anxiety, general pain, dizziness, and general discomfort. The positive effects of CBD have been reported by patients with POTS. CBD is not as side-effects-prone as other medications that are used to treat the symptoms.
Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response
COVID-19 has spread rapidly, highlighting the need to find new treatments. We report here that CBD, a compound found in cannabis plants, inhibits SARS/CoV-2 infection. CBD and its metabolite 7-OH-CBD but not congeneric cannabis cannabinoids potently inhibit SARS-CoV-2 replication within lung epithelial cell lines. CBD works after cellular infection, blocking viral gene expression and reversing many of the effects of SARS-2 on host gene transcript. CBD increases interferon production and regulates its antiviral signaling pathway. The SARS-CoV-2 incidence in a cohort of patients who had previously taken CBD was significantly lower than that of matched pairs or the general public. This study highlights CBD and its active metabolite 7-OH-CBD as possible therapeutic treatments and preventative agents for SARS-CoV-2 in the early stages.